Raphael Discografia Completa Torrent
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Raphael Discografia CompletaThe present invention relates to methods for preparing cardiovascular prostheses. More particularly, the present invention relates to a method for preparing cardiovascular prostheses wherein a polymeric substrate having a thermoplastic layer is subjected to hot air to form an adhesive for applying a polymeric coating to the substrate.
Artificial cardiovascular prostheses are widely employed in the repair of diseased or damaged vessels, such as arteries. Such a prosthesis is typically constructed from a tubular extrusion having a polymeric substrate, with the polymeric substrate including one or more layers of polymeric material. The polymeric material is usually polyethylene or polypropylene.
When using such a polymeric substrate to produce the cardiovascular prosthesis, at least one of the layers of polymeric material of the substrate must be thermally bonded to the substrate. The polymeric material layer is usually adhered to the substrate using an adhesive material. Once bonded, the multi-layer polymeric tubular substrate having the polymeric material layer can be molded to form the cardiovascular prosthesis. See for example, U.S. Pat. No. 4,270,143 to Ayers and U.S. Pat. No. 4,600,656 to Campagnuolo.
To optimize the mechanical properties of the polymeric material layer, it is preferable that the adhesion of the polymeric material layer be sufficient to withstand the stresses imposed on the polymeric material layer by the extrusion process and to withstand the stresses imposed on the prosthesis by the host artery. To increase the strength of the adhesive layer, the adhesion between the adhesive and substrate layer is preferably adequate to transfer stress stresses. To further improve adhesion, the polymeric substrate and adhesive layers are typically heated prior to the molding 0b46394aab
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